The University of Pennsylvania will host the official grand opening of the Artificial Intelligence-Driven RNA BioFoundry (AIRFoundry), a major new national resource at the intersection of artificial intelligence, bioengineering, and biotechnology. Funded by the National Science Foundation, the AIRFoundry is a state-of-the-art user facility designed to harness AI-driven discovery, high-throughput bioengineering, and advanced manufacturing to accelerate innovation in RNA-based technologies across human health, agriculture, environmental sustainability, and biotechnology manufacturing.