Discovering the Future of AI
Penn AI is pleased to announce the first four awardees for the Discovering the Future of AI awards. Fifty-four competitive applications were submitted in response to the request for proposals, representing creative and bold ideas in research and education across Penn’s schools.
In addition to the four awards totaling $450,000, an additional 31 faculty applicants representing eleven schools received awards for high performance computing needs supported by the Penn Advanced Research Computing Center (PARCC) for an estimated value of $852,000, bringing the total support to $1.3 million. Access to high-performance computing enables Penn researchers to run state-of-the-art AI models, analyze far larger datasets, and pursue bold, high-risk ideas without financial constraints.
The Discovering the Future award is designed to catalyze high-risk, high-reward research and education at the intersection of artificial intelligence and domain scholarship for the benefit of society.
We congratulate the following four awardees:
CASPER4D: Computer Assisted Surgical Performance Evaluation via Reconstruction

Daniel Hashimoto
Assistant Professor of Surgery, Perelman School of Medicine
(in collaboration with School of Engineering and Applied Sciences)
CASPER4D is a collaborative research project using AI to reconstruct four-dimensional surgical environments from standard video to assess skill, predict risk, and improve patient outcomes.
The Penn AI Pedagogy Initiative: Building Capacity for Meaningful and Responsible Adoption at Scale

Seiji Isotani
Associate Professor, Graduate School of Education
(in collaboration with School of Arts & Sciences)
The Penn AI Pedagogy Initiative supports faculty and students in co-designing AI-enhanced teaching practices, building a scalable framework for responsible AI adoption in education.
Molecule 3D Structure Informed Science Agentic LLM

Cesar de la Fuente
Presidential Associate Professor, Perelman School of Medicine (Microbiology)
(in collaboration with School of Engineering and Applied Sciences)
ApexMol will integrate language and 3D molecular structure to enable AI systems to reason about and design new biomolecules, accelerating discovery.
EchoMFM: A Multimodal Foundation Model for Automated Clinical Interpretation of Echocardiograms

Julio Chirinos Medina
Professor, Perelman School of Medicine (Cardiovascular Medicine)
EchoMFM will integrate imaging, EHR, reports, ECG, and MRI data to generate draft clinical interpretations and improve diagnostic efficiency.